medical5 min Read

Understanding Skin Aging and Effective Anti-Aging Interventions

Skin aging isn't just inevitable; it’s a battle between your genes (Intrinsic) and your environment (Extrinsic). In 2026, we don’t just ""treat"" wrinkles—we target the root causes.

Dr. Yeseul Moon
Dr. Yeseul Moon
Feb 20, 2026
Understanding Skin Aging and Effective Anti-Aging Interventions

Skin aging is a natural process influenced by both intrinsic and extrinsic factors. Intrinsic aging, also known as chronological aging, is genetically programmed and progresses with time, while extrinsic aging stems from environmental factors like UV exposure, pollution, and lifestyle habits. Here’s a concise overview of the mechanisms and corresponding management strategies for youthful, healthy skin.

Takeaway Effective anti-aging combats both natural decline and environmental damage. It requires a foundation of daily UV protection and topicals, supported by advanced treatments like lasers and injectables to actively rebuild the skin's structure.

Mechanisms of Skin Aging

Aging occurs through two main pathways: intrinsic (chronological) and extrinsic (environmental). As we age, cellular senescence stops cell growth and releases inflammatory factors, while oxidative stress from UV rays damages DNA. This leads to the breakdown of the extracellular matrix—specifically collagen and elastin fibers—causing the skin to lose strength, thin out, and develop wrinkles and sagging.

Prevention and Management Strategies

Effective management begins with daily UV protection, the most essential step in slowing aging. Topical treatments like retinoids and Vitamin C help boost collagen and neutralize damage. For more advanced rejuvenation, energy-based devices (Lasers, RF, HIFU) tighten deeper layers, while injectables like Hyaluronic Acid, Botulinum Toxin, and skin boosters (PLA, PCL, PN) restore volume and stimulate new collagen production.

Recommended Treatment

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Dr. Yeseul Moon

About Dr. Yeseul Moon

PICKLS Founder & Chief Director of WANNABE Clinic

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